ben's notes

ADHD

DSM Criteria #

Age of onset: <= 12 years Pervasiveness: symptoms present in >=2 settings

6 symptoms per category for children up to 16 years old, 5 symptoms for 17+

Core Symptoms #

Inattention:

  • failure to pay attention to details

Hyperactivity and impulsivity

Variability #

ADHD is best thought of dimensionally, since symptoms can present very differently:

  • types of symptoms
  • severity of symptoms
  • nature and degree of impairment
  • settings that symptoms present
    • example: only have inattention during school, but can focus when playing video games

Diagnosing ADHD #

  • typically done using parent and teacher rating scales combined with a clinical interview to assess onset
  • observation is valid but not practical due to cost
  • evaluate functioning in key developmental domains such as interpersonal relationships, academic progress, family dynamic
  • treatment planning: collect context and impact of symptoms

Gene Environment Interactions #

Genetic liability: heritability is .6-.9 (highly heritable)

  • Play a larger role than environment Experiential activators (i.e. environmental risk factors): prenatal alcohol, maternal stress during pregnancy, postnatal lead

Mechanisms of ADHD (Endophenotype) #

Attention #

Ability to maintain performance over time

  • Not related to orienting ability (aligning attention to single source of information)

Executive Function #

Executive function is a set of cognitive processes that allow an individual to produce meaningful, goal oriented behavior by selecting relevant thoughts and actions.

Executive function includes three main components:

  1. Working memory enables the ability to keep multiple things in the mind at once.
  2. Response suppression enables the ability to interrupt a response if the situation calls for it. For example, children should be able to wait their turn to get food during recess (initial response: immediately run out and play)
  3. Set shifting (cognitive flexibility) enables the ability to shift mental focus within or between tasks, and alternate between tasks

Motivation and reinforcement #

specific reward system impairment; sharp decrease in interest after long wait times

Temporal information processing #

greater variability in estimating and perceiving time

Treatment and Intervention #

Medication: symptom management (but not cure)

  • requires existing support from parents/mentors, and willingness to improve symptoms
  • greatest effect on ADHD symptoms Parent management training: use operant conditioning to reward positive behavior and discourage others Teacher/peer directed interventions: evidence-based intervention where children are paired with other kids with ADHD who have been successful with managing symptoms Psychoeducation: tell parents what ADHD is, encourage compassion+motivation to implement strategies Adolescent-directed behavior treatment:
  • teach kids executive control skills and how to apply them to daily life
  • provide regular monitoring and reinforcement
  • promote autonomy via healthy relationship with parents
  • greatest effect on functional impairment